SALT INFORMATION
Gliclazide 80 MG + Metformin 500 MG

GLICLAZIDE 80 MG
Use
Gliclazide is used in the treatment of Type 2 Diabetes, it is used when diabetes cannot be controlled by proper dietary management and exercise or when insulin therapy is not appropriate. It works mostly by increasing the release of insulin.
Common Side Effect
Nausea, Skin rash, Itching, Vomiting, Fever, Weakness, Dizziness, Drowsiness, Headache, Sweating.
Precaution
Contraindicated in Type 1 diabetes, Hypersensitivity to sulfonylureas, in severe renal or hepatic failure, in Pregnancy and lactation.
Class of Drug - Anti-Diabetic (IInd Generation Sulphonylurea Oral Hypoglycaemic Agent)
Route of Administration - Oral
Bioavailability - Rapidly Absorbed
Biological Half Life - 10.4 Hours
Excretion - Kidneys (60-70%), Feces (10-20%)

METFORMIN 500 MG
Use
Metformin is the first-line medication for the treatment of type 2 diabetes. It is also used in the treatment of polycystic ovary syndrome.
Common Side Effect
Includes gastrointestinal irritation, diarrhea, cramps, nausea, vomiting, increased flatulence; metformin is more commonly associated with gastrointestinal side effects than most other antidiabetic drugs.
Precaution
It should not be used in those with significant liver disease or kidney problems.
Class of Drug - Biguanide Class
Route of Administration - Oral
Bioavailability - 50–60%
Biological Half Life - 4-8.7 Hours
Excretion - Urine 90%